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Inducing Cancer Cell Death by Inhibition of GPCR Signaling Based on the Tumor Microenvironment
SUMMARY Damien Thevenin, at Lehigh University has developed a compound, pH (low) insertion peptide (pHLIP), which can selectively target tumors based on their low extracellular pH, while sparing healthy tissues and preventing off-target toxicity. This delivery peptide can be conjugated to soluble peptides capable of inhibiting the activity of G-pro...
Published: 12/3/2015   |   Inventor(s): Damien Thevenin
Category(s): Oncology, Therapeutics