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Force Spectroscopy Platform for DNA Sequencing
SUMMARY Lehigh University has developed a technique based on molecular mechanics which detects changes in molecular elasticity of a single DNA fragment upon conversion from a single-stranded to double-stranded form. Essentially this technology is sequencing by synthesis and its advantages are that one could use native dNTPs and substrates and not ...
Published: 2/20/2009   |   Inventor(s): Dmitri Vezenov
Keywords(s): Biomedical Applications, Biosensors, DNA sequencing, Force Spectroscopy, Microarrays
Category(s): Life Sciences